Synthesis of biodegradable polymers based on carbamide and formaldehyde

Abstract

Biodegradation of polymersof spatial structure is complicated at the impact of soil destructive microorganisms and biodegradation requires long time. We have implemented target-oriented synthesis of a polymer to receive linear structure polymers where labile peptide bonds are preserved. To realize target-oriented synthesis of polymers and to determine reaction mechanism and optimal conditions of synthesis we studied the process kinetics and reaction regularities - reaction temperature, pH of reaction medium, duration, components ratio, concentration, reaction speed constant and activation energy. The Arrhenius factor and succession of introduction of initial components to the reaction medium were computed, catalyst nature and other properties were determined. High effect of prolongation was achieved, when carbamide and formaldehyde molar ratio was 1:1. In this case linear structure polymeris formed wherepeptide bonds– CO – NH –) are preserved. The simplified structure of linear polymer isexpressed as followed: – HNCONHCH2– [NHCONHCH2]n– HNCONHCH2–